Thp1-luciatm nf-κb cells
WebIn general, THP-1 cells exhibit a large, round, single-cell morphology. The cells were derived from the peripheral blood of a 1-year-old human male with acute monocytic leukemia. … WebTHP1-Lucia™ NF-κB Cells. THP1-Lucia™ NF-κB Cells. Catalog No. thpl-nfkb. NF-κB Luc Reporter Monocytes. Read more Show less. Pack Size. 3-7 x 10e6 cells; Quantity. Add to Cart. Submit for Quotation Add To Wishlist. Share. Login to purchase * Free Delivery for Orders SGD$250 (excl. GST) & Above. Brand: Specifications;
Thp1-luciatm nf-κb cells
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WebNF-κB is a pleiotropic transcription factor with key functions in the intestinal immune system. NF-κB family members control transcriptional activity of various promoters of proinflammatory cytokines, cell surface receptors, transcription factors, and adhesion molecules that are involved in intestinal inflammation. The perpetuated activation of NF … WebThis luciferase reporter cell line was derived from parental line TIB-202 by stably expressing firefly luciferase gene (luc2) under control of a NF- κB promoter through lentiviral …
WebMay 1, 2008 · We chose 2 cell lines as reference for the assay: BL41, a Burkitt lymphoma line with relatively low NF-κB activity, and IARC-171, an Epstein-Barr virus (EBV) immortalized line derived from the same patient. EBV activates NF-κB during B-cell immortalization, so IARC-171 cells represent a positive control for a B-cell high in NF-κB. WebNF-kB-SEAP and IRF-Lucia luciferase Reporter Monocytes. THP1-Dual™ cells were derived from the human THP-1 monocyte cell line by stable integration of two inducible reporter constructs.. As a result, THP1-Dual™ cells allow the simultaneous study of the NF-κB pathway, by monitoring the activity of SEAP, and the IRF pathway, by assessing the …
WebApr 14, 2024 · Isolated murine neutrophils were resuspended in serum-free RPMI-1640 medium containing 1% P/S at 106 cells/mL. 100 μL cells were added to the upper well of each Transwell chamber (5 μm pore size, Corning) placed in a 24-well plate, and 300 μL serum-freed cell supernatant from the pretreated primary macrophages were added to … WebApr 13, 2024 · Severe bacterial pneumonia leads to acute respiratory distress syndrome (ARDS), with a high incidence rate and mortality. It is well-known that continuous and dysregulated macrophage activation is vital for aggravating the progression of pneumonia. Here, we designed and produced an antibody-like molecule, peptidoglycan recognition …
WebTHP1-Lucia™ cells were specifically designed for monitoring the NF-κB signal transduction pathway in a physiologically relevant cell line. THP1-Lucia™ were derived from the human …
WebTHP1-Blue™ were derived from the human THP-1 monocyte cell line by stable integration of an NF-κB-inducible SEAP reporter construct. As a result, THP1-Blue™ NF-κB cells allow … new website liveWebNov 23, 2024 · Figure 1 LUBAC is necessary for the TCR-mediated NF-κB activation pathway.(A) Parental Jurkat cells, HOIP-deficient cells (RNF31-KO), or WT-HOIP-restored … mike francis shalon latourWebAug 25, 2009 · A molecular link between TCR stimulation and NF-κB activation in T cells is the hematopoietic progenitor kinase 1 (HPK1). HPK1 comprises an N-terminal kinase domain and a C-terminal citron homology (CNH) domain ().Antigen receptor cross-linking leads to activation of HPK1 in T and B cells (20, 21).HPK1 activation involves relocation to … mike francis flashes of lifeWebThe nuclear factor-κB (NF-κB) plays a central role in the activation and survival of lymphocytes. NF-κB, therefore, is pivotal for acquired immunity, but the dysregulation of … new website launch wordingWebFeb 26, 2016 · The NF-κB transcription factor is the master regulator of the inflammatory response and is essential for the homeostasis of the immune system. NF-κB regulates the transcription of genes that control inflammation, immune cell development, cell cycle, proliferation, and cell death. The fundamental role that NF-κB plays in key physiological … mike frankel bay area news groupWeb2 days ago · Taken together, these data indicate that the IL-346 17A/Act1/TRAF6/NF-κB axis is a vital signaling pathway for Ncs-induced mitochondrial 347 apoptosis of CC cells. 348 … new websites 2021WebApr 12, 2024 · DCs (5 × 10 6 cells) were pretreated with 100 nM TAK-242 (TLR4 inhibitor, MedChemExpress, USA) or 20 mM PDTC (NF-κB inhibitor, MedChemExpress, USA) for 2 … new website press release sample